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| 카탈로그 번호 | HC155015 |
|---|---|
| 설명 |
Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709) [1A709] (HC155015) is a mouse monoclonal antibody detecting SLC22A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, IHC, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | 1A709 |
| 면역원 | E. coli - derived recombinant human SLC22A2/OCT2 (Gly44-Asp150). |
| 타겟 | Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | O15244 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Solute carrier family 22 member 2 (SLC22A2/OCT2) is a ~62 kDa protein. Electrogenic voltage-dependent transporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics. Functions as a Na(+)-independent, bidirectional uniporter. Cation cellular uptake or release is driven by the electrochemical potential, i.e. membrane potential and concentration gradient. However, may also engage electroneutral cation exchange when saturating concentrations of cation substrates are reached. 1. Gorboulev, V. et al. (1997) DNA and cell biology 16, 871-81. PMID: 9260930 2. Busch, AE. et al. (1998) Molecular pharmacology 54, 342-52. PMID: 9687576 3. Winter, TN. et al. (2011) Molecular pharmaceutics 8, 133-42. PMID: 21128598 4. Urakami, Y. et al. (2004) Pharmaceutical research 21, 976-81. PMID: 15212162 5. Kimura, N. et al. (2005) Pharmaceutical research 22, 255-9. PMID: 15783073 6. Amphoux, A. et al. (2006) Neuropharmacology 50, 941-52. PMID: 16581093 7. Taubert, D. et al. (2007) PloS one 2, e385. PMID: 17460754 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A709)
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