Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

Name: Anti-Human SLC25A12 Polyclonal Antibody
Brand: abinScience
SKU: HF639014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HF639014

설명

Anti-Human SLC25A12 Polyclonal Antibody (HF639014) is a rabbit polyclonal antibody detecting SLC25A12 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SLC25A12 (Gly11-Gln311).

타겟

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial, Araceli hiperlarga, Aralar, Aralar1, Mitochondrial aspartate glutamate carrier 1, Solute carrier family 25 member 12, SLC25A12, AGC1, ARALAR1

정제

Purified by antigen affinity column.

등록번호

O75746

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial is a ~74 kDa protein. Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA).

1. Palmieri, L. et al. (2001) The EMBO journal 20, 5060-9. PMID: 11566871

2. Wibom, R. et al. (2009) The New England journal of medicine 361, 489-95. PMID: 19641205

3. Falk, MJ. et al. (2014) JIMD reports 14, 77-85. PMID: 24515575

4. Porcelli, V. et al. (2024) Biochimica et biophysica acta. Bioenergetics 1865, 149487. PMID: 38945283

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-SLC25A12 polyclonal antibody at SLC25A12 on various samples.
Lane 1: Jurkat cell lysate
Lane 2: A431 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse skeletal muscle lysate
Lane 5: Rat brain lysate
Lane 6: Rat skeletal muscle lysate

참고 문헌

데이터시트

Anti-Human SLC25A12 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

개요

이미지

참고 문헌

데이터시트

SDS