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| 카탈로그 번호 | HP731014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SLC25A46 (Glu335-Gly381). | ||||||||
| 타겟 | TB1, Solute carrier family 25 member 46, SLC25A46 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q96AG3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Mitochondrial outer membrane protein SLC25A46 is a ~46 kDa protein. Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization. May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane. Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission. 1. Abrams, AJ. et al. (2015) Nature genetics 47, 926-32. PMID: 26168012 2. Janer, A. et al. (2016) EMBO molecular medicine 8, 1019-38. PMID: 27390132 3. Wan, J. et al. (2016) Brain : a journal of neurology 139, 2877-2890. PMID: 27543974 | ||||||||
| 참고사항 | For research use only. |
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