

| 카탈로그 번호 | HP576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SLC30A6 Polyclonal Antibody (HP576014) is a rabbit polyclonal antibody detecting SLC30A6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SLC30A6 (Ser247-Asp334). | ||||||||
| 타겟 | ZnT-6, Solute carrier family 30 member 6, Zinc transporter 6, ZNT6, SLC30A6 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6NXT4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Zinc transporter 6 (SLC30A6) is a ~51 kDa protein. Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis. 1. Suzuki, T. et al. (2005) The Journal of biological chemistry 280, 30956-62. PMID: 15994300 2. Ohana, E. et al. (2009) The Journal of biological chemistry 284, 17677-86. PMID: 19366695 3. Fukunaka, A. et al. (2009) The Journal of biological chemistry 284, 30798-806. PMID: 19759014 4. Wagatsuma, T. et al. (2022) The Journal of biological chemistry 298, 102011. PMID: 35525268 | ||||||||
| 참고사항 | For research use only. |
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