Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

Name: Anti-Human SLC39A7 Polyclonal Antibody
Brand: abinScience
SKU: HD636014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HD636014

설명

Anti-Human SLC39A7 Polyclonal Antibody (HD636014) is a rabbit polyclonal antibody detecting SLC39A7. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SLC39A7 (Gly30-Thr133).

타겟

HKE4, Histidine-rich membrane protein Ke4, RING5, Really interesting new gene 5 protein, SLC39A7, Solute carrier family 39 member 7, ZIP7, Zinc transporter SLC39A7, Zrt-, Irt-like protein 7

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q92504

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Zinc transporter SLC39A7 is a ~50 kDa protein. Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling. Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle.

1. Taylor, KM. et al. (2004) The Biochemical journal 377, 131-9. PMID: 14525538

2. Huang, L. et al. (2005) The Journal of biological chemistry 280, 15456-63. PMID: 15705588

3. Nimmanon, T. et al. (2017) Metallomics : integrated biometal science 9, 471-481. PMID: 28205653

4. Woodruff, G. et al. (2018) Molecular pharmacology 94, 1092-1100. PMID: 29980658

5. Taylor, KM. et al. (2012) Science signaling 5, ra11. PMID: 22317921

6. Anzilotti, C. et al. (2019) Nature immunology 20, 350-361. PMID: 30718914

7. Fauster, A. et al. (2019) Cell death and differentiation 26, 1138-1155. PMID: 30237509

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human SLC39A7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

개요

이미지

참고 문헌

데이터시트

SDS