

| 카탈로그 번호 | HA176014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SLC9A9 Polyclonal Antibody (HA176014) is a rabbit polyclonal antibody detecting SLC9A9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SLC9A9. | ||||||||
| 타겟 | Sodium/hydrogen exchanger 9, Na(+)/H(+) exchanger 9, NHE-9, Solute carrier family 9 member 9, SLC9A9, NHE9, Nbla00118 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8IVB4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Sodium/hydrogen exchanger 9 (SLC9A9) is a ~72 kDa protein. Endosomal Na(+), K(+)/H(+) antiporter. Mediates the electroneutral exchange of endosomal luminal H(+) for a cytosolic Na(+) or K(+) (Probable). By facilitating proton efflux, SLC9A9 counteracts the acidity generated by vacuolar (V)-ATPase, thereby limiting luminal acidification. Regulates organellar pH and consequently, e.g., endosome maturation and endocytic trafficking of plasma membrane receptors and neurotransporters. Promotes the recycling of transferrin receptors back to the cell surface to facilitate additional iron uptake in the brain. 1. Nakamura, N. et al. (2005) The Journal of biological chemistry 280, 1561-72. PMID: 15522866 2. Kondapalli, KC. et al. (2013) Nature communications 4, 2510. PMID: 24065030 3. Beydoun, R. et al. (2017) The Journal of biological chemistry 292, 4293-4301. PMID: 28130443 | ||||||||
| 참고사항 | For research use only. |
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