

| 카탈로그 번호 | HF704014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SLU7 Polyclonal Antibody (HF704014) is a rabbit polyclonal antibody detecting SLU7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SLU7 (Met28-Tyr173). | ||||||||
| 타겟 | Pre-mRNA-splicing factor SLU7, hSlu7, SLU7 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O95391 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pre-mRNA-splicing factor SLU7 is a ~68 kDa protein. Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. 1. Chua, K. et al. (1999) Genes & development 13, 841-50. PMID: 10197984 2. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 3. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154 | ||||||||
| 참고사항 | For research use only. |
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