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| 카탈로그 번호 | HF679014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SORBS2 (Lys865-Thr1001). | ||||||||
| 타겟 | Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin, KIAA0777, ARGBP2, SORBS2, Arg-binding protein 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O94875 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Sorbin and SH3 domain-containing protein 2 (SORBS2) is a ~124 kDa protein. Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 1. Taieb, D. et al. (2008) Cancer research 68, 4588-96. PMID: 18559503 | ||||||||
| 참고사항 | For research use only. |
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