

| 카탈로그 번호 | HC428014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SOS1 Polyclonal Antibody (HC428014) is a rabbit polyclonal antibody detecting SOS1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SOS1 (Gln566-Arg1046). | ||||||||
| 타겟 | SOS1, Son of sevenless homolog 1, SOS-1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q07889 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Son of sevenless homolog 1 (SOS1) is a ~152 kDa protein. Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3/ERK1 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity. 1. Chardin, P. et al. (1993) Science (New York, N.Y.) 260, 1338-43. PMID: 8493579 2. Modzelewska, K. et al. (2007) Molecular and cellular biology 27, 3695-707. PMID: 17339331 | ||||||||
| 참고사항 | For research use only. |
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