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| 카탈로그 번호 | HF883014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SOX30 Polyclonal Antibody (HF883014) is a rabbit polyclonal antibody detecting SOX30 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SOX30 (Thr292-Gly403). | ||||||||
| 타겟 | Transcription factor SOX-30, SOX30 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O94993 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Transcription factor SOX-30 (SOX30) is a ~81 kDa protein. Acts both as a transcriptional activator and a repressor. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif. Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling. 1. Osaki, E. et al. (1999) Nucleic acids research 27, 2503-10. PMID: 10359848 2. Han, F. et al. (2018) EBioMedicine 31, 253-266. PMID: 29739711 | ||||||||
| 참고사항 | For research use only. |
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