Anti-Human SPART Polyclonal Antibody (HC761014)

Name: Anti-Human SPART Polyclonal Antibody
Brand: abinScience
SKU: HC761014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HC761014

설명

Anti-Human SPART Polyclonal Antibody (HC761014) is a rabbit polyclonal antibody detecting SPART. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SPART (Gly198-Gln336).

타겟

KIAA0610, SPART, SPG20, Spartin, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q8N0X7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Spartin is a ~72 kDa protein. Lipophagy receptor that plays an important role in lipid droplet (LD) turnover in motor neurons. Localizes to LDs and interacts with components of the autophagy machinery, such as MAP1LC3A/C proteins to deliver LDs to autophagosomes for degradation via lipophagy. Lipid transfer protein required for lipid droplet degradation, including by lipophagy. Can bind and transfer all lipid species found in lipid droplets, from phospholipids to triglycerides and sterol esters but the direction of lipid transfer by spartin and its cargos are unknown. May be implicated in endosomal trafficking, or microtubule dynamics, or both.

1. Chung, J. et al. (2023) Nature cell biology 25, 1101-1110. PMID: 37443287

2. Wan, N. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2314093121. PMID: 38190532

3. Renvoisé, B. et al. (2010) Molecular biology of the cell 21, 3293-303. PMID: 20719964

참고사항

For research use only

이미지

Western blot

Western blot analysis was performed using anti-SPART polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: PANC1 cell lysate
Lane 3: HL-60 cell lysate
Lane 4: MDA-MB-231 cell lysate
Lane 5: K562 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse heart lysate
Lane 8: Rat heart lysate
Lane 9: Mouse brain lysate
Lane 10: Rat brain lysate
Lane11: Mouse spleen lysate

참고 문헌

데이터시트

Anti-Human SPART Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SPART Polyclonal Antibody (HC761014)

개요

이미지

참고 문헌

데이터시트

SDS