Anti-Human SPRR2A Polyclonal Antibody (HA621014)

Name: Anti-Human SPRR2A Polyclonal Antibody
Brand: abinScience
SKU: HA621014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA621014

설명

Anti-Human SPRR2A Polyclonal Antibody (HA621014) is a rabbit polyclonal antibody detecting Small proline-rich protein 2A; SPR-2A; 2-1; SPRR2A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human SPRR2A (Ser2-Lys72).

타겟

Small proline-rich protein 2A; SPR-2A; 2-1; SPRR2A

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P35326, P35325

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Small proline-rich protein 2A (SPRR2A) is a ~7 kDa protein. Gut bactericidal protein that selectively kills Gram-positive bacteria by binding to negatively charged lipids on bacterial membranes, leading to bacterial membrane permeabilization and disruption. Specifically binds lipids bearing negatively charged headgroups, such as phosphatidic acid, phosphatidylserine (PS), cardiolipin (CL), and phosphatidylinositol phosphates, but not to zwitterionic or neutral lipids. Induced by type-2 cytokines in response to helminth infection and is required to protect against helminth-induced bacterial invasion of intestinal tissue. May also be involved in the development of the cornified envelope of squamous epithelia; however, additional evidences are required to confirm this result in vivo.

1. Hu, Z. et al. (2021) Science (New York, N.Y.) 374, eabe6723. PMID: 34735226

2. Gibbs, S. et al. (1993) Genomics 16, 630-7. PMID: 8325635

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human SPRR2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SPRR2A Polyclonal Antibody (HA621014)

개요

이미지

참고 문헌

데이터시트

SDS

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