Anti-Human SRY Polyclonal Antibody (HC271014)

Name: Anti-Human SRY Polyclonal Antibody
Brand: abinScience
SKU: HC271014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC271014

설명

Anti-Human SRY Polyclonal Antibody (HC271014) is a rabbit polyclonal antibody detecting SRY in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SRY (Met1-Leu204).

타겟

TDF, Sex-determining region Y protein, Testis-determining factor, SRY

정제

Purified by antigen affinity column.

등록번호

Q05066

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Sex-determining region Y protein (SRY) is a ~23 kDa protein. Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.

1. Murphy, EC. et al. (2001) Journal of molecular biology 312, 481-99. PMID: 11563911

2. Oh, HJ. et al. (2006) Molecular and cellular endocrinology 247, 47-52. PMID: 16414182

3. Polanco, JC. et al. (2007) Developmental biology 302, 13-24. PMID: 16996051

4. Desclozeaux, M. et al. (1998) The Journal of biological chemistry 273, 7988-95. PMID: 9525897

5. Ferrari, S. et al. (1992) The EMBO journal 11, 4497-506. PMID: 1425584

6. Phillips, NB. et al. (2004) Biochemistry 43, 7066-81. PMID: 15170344

7. Giese, K. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 3368-72. PMID: 8159753

8. King, CY. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 11990-4. PMID: 8265659

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human SRY Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SRY Polyclonal Antibody (HC271014)

개요

이미지

참고 문헌

데이터시트

SDS