Anti-Human SUZ12 Polyclonal Antibody (HC259014)

Name: Anti-Human SUZ12 Polyclonal Antibody
Brand: abinScience
SKU: HC259014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC259014

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SUZ12 (Lys587-Gly691).

타겟

SUZ12, Polycomb protein SUZ12, Joined to JAZF1 protein, CHET9, KIAA0160, ChET 9 protein, Suppressor of zeste 12 protein homolog, Chromatin precipitated E2F target 9 protein, JJAZ1

정제

Purified by antigen affinity column.

등록번호

Q15022

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Polycomb protein SUZ12 is a ~83 kDa protein. Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548

2. Kirmizis, A. et al. (2004) Genes & development 18, 1592-605. PMID: 15231737

3. Pasini, D. et al. (2004) The EMBO journal 23, 4061-71. PMID: 15385962

4. Bracken, AP. et al. (2006) Genes & development 20, 1123-36. PMID: 16618801

5. Bracken, AP. et al. (2007) Genes & development 21, 525-30. PMID: 17344414

6. Sarma, K. et al. (2008) Molecular and cellular biology 28, 2718-31. PMID: 18285464

7. Imagawa, E. et al. (2017) Human mutation 38, 637-648. PMID: 28229514

8. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137

9. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557

10. Cao, R. et al. (2002) Science (New York, N.Y.) 298, 1039-43. PMID: 12351676

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human SUZ12 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SUZ12 Polyclonal Antibody (HC259014)

개요

이미지

참고 문헌

데이터시트

SDS

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