Anti-Human TARBP2 Polyclonal Antibody (HS711014)

Name: Anti-Human TARBP2 Polyclonal Antibody
Brand: abinScience
SKU: HS711014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HS711014

설명

Anti-Human TARBP2 Polyclonal Antibody (HS711014) is a rabbit polyclonal antibody detecting TARBP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TARBP2 (Thr264-Lys366).

타겟

RISC-loading complex subunit TARBP2, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2, TRBP

정제

Purified by antigen affinity column.

등록번호

Q15633

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

RISC-loading complex subunit TARBP2 is a ~39 kDa protein. Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.

1. Chendrimada, TP. et al. (2005) Nature 436, 740-4. PMID: 15973356

2. Haase, AD. et al. (2005) EMBO reports 6, 961-7. PMID: 16142218

3. Gregory, RI. et al. (2005) Cell 123, 631-40. PMID: 16271387

4. Maniataki, E. et al. (2005) Genes & development 19, 2979-90. PMID: 16357216

5. Lee, Y. et al. (2006) The EMBO journal 25, 522-32. PMID: 16424907

6. Kok, KH. et al. (2007) The Journal of biological chemistry 282, 17649-57. PMID: 17452327

7. MacRae, IJ. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 512-7. PMID: 18178619

8. Fukunaga, R. et al. (2012) Cell 151, 533-46. PMID: 23063653

9. Ling, T. et al. (2019) Molecular immunology 109, 116-125. PMID: 30927622

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human TARBP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TARBP2 Polyclonal Antibody (HS711014)

개요

이미지

참고 문헌

데이터시트

SDS