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| 카탈로그 번호 | HP216014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TBC1D23 (Gly15-Lys306). | ||||||||
| 타겟 | NS4ATP1, TBC1D23, TBC1 domain family member 23, HCV non-structural protein 4A-transactivated protein 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9NUY8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | TBC1 domain family member 23 (TBC1D23) is a ~78 kDa protein. Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. 1. Ivanova, EL. et al. (2017) American journal of human genetics 101, 428-440. PMID: 28823707 2. Shin, JJH. et al. (2017) Nature cell biology 19, 1424-1432. PMID: 29084197 3. Navarro Negredo, P. et al. (2018) Nature communications 9, 596. PMID: 29426865 | ||||||||
| 참고사항 | For research use only. |
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