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| 카탈로그 번호 | HP228013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, IF, IP | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG | ||||
| 클론 ID | SAA0234 | ||||
| 타겟 | TDRD3, Tudor domain-containing protein 3 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9H7E2 | ||||
| RRID | Anti-Human TDRD3 IP Antibody (SAA0234) (abinScience Cat# HP228013, RRID:AB_3729768) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Tudor domain-containing protein 3 (TDRD3) is a ~73 kDa protein. Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. 1. Côté, J. et al. (2005) The Journal of biological chemistry 280, 28476-83. PMID: 15955813 2. Yang, Y. et al. (2010) Molecular cell 40, 1016-23. PMID: 21172665 3. Deater, M. et al. (2022) PLoS pathogens 18, e1010249. PMID: 35085371 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human TDRD3 IP Antibody (SAA0234)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
