Anti-Human THOC7 Polyclonal Antibody (HA527014)

Name: Anti-Human THOC7 Polyclonal Antibody
Brand: abinScience
SKU: HA527014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA527014

설명

Anti-Human THOC7 Polyclonal Antibody (HA527014) is a rabbit polyclonal antibody detecting THOC7 in ELISA, IHC, WB. Suitable for Xenopus tropicalis, Xenopus laevis, Bovine, and Mus musculus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human THOC7 (Met1-Pro204).

타겟

THOC7

정제

Purified by antigen affinity column.

등록번호

Q6I9Y2

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

THO complex subunit 7 homolog, Functional spliceosome-associated protein 24, fSAP24, Ngg1-interacting factor 3-like protein 1-binding protein 1, NIF3L1-binding protein 1, hTREX30, THOC7, NIF3L1BP1

배경

THO complex subunit 7 (THOC7) is a ~23 kDa protein. Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA. Plays a key structural role in the oligomerization of the THO-DDX39B complex. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway.

1. Guo, S. et al. (2005) Cancer research 65, 3011-6. PMID: 15833825

2. Masuda, S. et al. (2005) Genes & development 19, 1512-7. PMID: 15998806

3. Cheng, H. et al. (2006) Cell 127, 1389-400. PMID: 17190602

4. Chi, B. et al. (2013) Nucleic acids research 41, 1294-306. PMID: 23222130

5. Pühringer, T. et al. (2020) eLife 9. PMID: 33191911

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-THOC7 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse skin lysate

참고 문헌

데이터시트

Anti-Human THOC7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human THOC7 Polyclonal Antibody (HA527014)

개요

이미지

참고 문헌

데이터시트

SDS

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