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| 카탈로그 번호 | HF782013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human TIMP1 Recombinant Antibody (2PC10) (HF782013) is a mouse monoclonal antibody detecting TIMP1 in Blocking, ELISA. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||
| 응용 분야 | Blocking, ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | 2PC10 | ||||
| 타겟 | Erythroid-potentiating activity, TIMP, EPA, TIMP1, Metalloproteinase inhibitor 1, TIMP-1, Fibroblast collagenase inhibitor, Collagenase inhibitor, CLGI, Tissue inhibitor of metalloproteinases 1 | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P01033 | ||||
| RRID | Anti-Human TIMP1 Antibody (2PC10) (abinScience Cat# HF782013, RRID:AB_3725813) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Metalloproteinase inhibitor 1 (TIMP1) is a ~23 kDa protein. Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human TIMP1 Antibody (2PC10)
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