Anti-Human TMED10 Polyclonal Antibody (HW693014)

Name: Anti-Human TMED10 Polyclonal Antibody
Brand: abinScience
SKU: HW693014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HW693014

설명

Anti-Human TMED10 Polyclonal Antibody (HW693014) is a rabbit polyclonal antibody detecting TMED10 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TMED10 (Ile32-Lys133).

타겟

S31I125, Tmp-21-I, Transmembrane protein Tmp21, Transmembrane emp24 domain-containing protein 10, TMP21, TMED10, 21 kDa transmembrane-trafficking protein, p23, S31III125, Protein TMED10, p24delta1, p24 family protein delta-1, p24delta

정제

Purified by antigen affinity column.

등록번호

P49755

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Transmembrane emp24 domain-containing protein 10 (TMED10) is a ~24 kDa protein. Cargo receptor involved in protein vesicular trafficking and quality control in the endoplasmic reticulum (ER) and Golgi. The p24 protein family is a group of transmembrane proteins that bind coat protein complex I/COPI and coat protein complex II/COPII involved in vesicular trafficking between the membranes. Acts at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and involved in vesicle coat formation at the cytoplasmic side. Mainly functions in the early secretory pathway and cycles between the ER, ER-Golgi intermediate compartment (ERGIC) and Golgi, mediating cargo transport through COPI and COPII-coated vesicles. In COPII vesicle-mediated anterograde transport, involved in the transport of GPI-anchored proteins by acting together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER.

1. Bremser, M. et al. (1999) Cell 96, 495-506. PMID: 10052452

2. Gommel, DU. et al. (2001) The EMBO journal 20, 6751-60. PMID: 11726511

3. Chen, F. et al. (2006) Nature 440, 1208-12. PMID: 16641999

4. Vetrivel, KS. et al. (2007) Molecular neurodegeneration 2, 4. PMID: 17288597

5. Luo, R. et al. (2009) Cellular signalling 21, 1169-79. PMID: 19296914

6. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317

7. Luo, W. et al. (2011) Journal of neurochemistry 117, 71-81. PMID: 21219331

8. Nagae, M. et al. (2016) Journal of molecular biology 428, 4087-4099. PMID: 27569046

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human TMED10 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TMED10 Polyclonal Antibody (HW693014)

개요

이미지

참고 문헌

데이터시트

SDS