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| 카탈로그 번호 | HA136013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse | ||||
| 응용 분야 | ELISA, FCM, SPR | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1912 | ||||
| 타겟 | TMEM106B, Transmembrane protein 106B | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9NUM4, Q80X71 | ||||
| RRID | Anti-Human TMEM106B Antibody (SAA1912) (abinScience Cat# HA136013, RRID:AB_3727676) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Transmembrane protein 106B (TMEM106B) is a ~31 kDa protein. In neurons, involved in the transport of late endosomes/lysosomes. May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking. May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites. 1. Stagi, M. et al. (2014) Molecular and cellular neurosciences 61, 226-40. PMID: 25066864 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human TMEM106B Antibody (SAA1912)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
