Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324) (HT176013)

Name: Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324)
Brand: abinScience
SKU: HT176013
Price: 191 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HT176013

설명

Anti-Human TMPRSS2 Nanobody (SAA2324) [SAA2324] (HT176013) is a human monoclonal antibody detecting TMPRSS2 in ELISA, Inhibition. Suitable for Human.

종 반응성

Alpaca

응용 분야

ELISA, Inhibition

숙주 종

Human

클론성

Monoclonal

이소타입

VHH-His

클론 ID

SAA2324

타겟

Transmembrane protease serine 2, EC:3.4.21.122, Serine protease 10, Transmembrane protease serine 2 non-catalytic chain, Transmembrane protease serine 2 catalytic chain, TMPRSS2, PRSS10

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by Nickel column

등록번호

O15393

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Transmembrane protease serine 2 (TMPRSS2) is a ~53 kDa protein. Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.