Anti-Human TRIM29 Polyclonal Antibody (HC430024)

Name: Anti-Human TRIM29 Polyclonal Antibody
Brand: abinScience
SKU: HC430024
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC430024

설명

Anti-Human TRIM29 Polyclonal Antibody (HC430024) is a rabbit polyclonal antibody detecting TRIM29. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TRIM29 (Glu170-Lys281).

타겟

ATDC, Ataxia telangiectasia group D-associated protein, TRIM29, Tripartite motif-containing protein 29

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q14134

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Tripartite motif-containing protein 29 (TRIM29) is a ~65 kDa protein. Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human TRIM29 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TRIM29 Polyclonal Antibody (HC430024)

개요

이미지

참고 문헌

데이터시트

SDS