Anti-Human TRIM33 Polyclonal Antibody (HP145014)

Name: Anti-Human TRIM33 Polyclonal Antibody
Brand: abinScience
SKU: HP145014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HP145014

설명

Anti-Human TRIM33 Polyclonal Antibody (HP145014) is a rabbit polyclonal antibody detecting TRIM33 in ELISA, IHC, WB. Suitable for Human, Mouse, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TRIM33 (Asp882-Ala1087).

타겟

TRIM33, RFG7, KIAA1113, RET-fused gene 7 protein, Tripartite motif-containing protein 33, RING-type E3 ubiquitin transferase TRIM33, E3 ubiquitin-protein ligase TRIM33, Protein Rfg7, TIF1-gamma, Ectodermin homolog, TIF1G, Transcription intermediary factor 1-gamma

정제

Purified by antigen affinity column.

등록번호

Q9UPN9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

E3 ubiquitin-protein ligase TRIM33 is a ~122 kDa protein. Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade.

1. He, W. et al. (2006) Cell 125, 929-41. PMID: 16751102

참고사항

For research use only.

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