

| 카탈로그 번호 | HS845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human TRIP11 Polyclonal Antibody (HS845014) is a rabbit polyclonal antibody detecting TRIP11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TRIP11 (Gln14-Tyr148). | ||||||||
| 타겟 | TRIP-11, CEV14, TR-interacting protein 11, Thyroid receptor-interacting protein 11, Golgi-associated microtubule-binding protein 210, Clonal evolution-related gene on chromosome 14 protein, Trip230, TRIP11, GMAP-210 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15643 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Thyroid receptor-interacting protein 11 (TRIP11) is a ~227 kDa protein. Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. 1. Sato, K. et al. (2015) Molecular biology of the cell 26, 537-53. PMID: 25473115 2. Wehrle, A. et al. (2019) JCI insight 4. PMID: 30728324 3. Roboti, P. et al. (2015) Journal of cell science 128, 1595-606. PMID: 25717001 | ||||||||
| 참고사항 | For research use only. |
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