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| 카탈로그 번호 | HF706014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human TTC4 Polyclonal Antibody (HF706014) is a rabbit polyclonal antibody detecting TTC4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TTC4 (Ile231-Arg387). | ||||||||
| 타겟 | Tetratricopeptide repeat protein 4, TPR repeat protein 4, TTC4, My044 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O95801 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Hsp70/Hsp90 co-chaperone CNS1 homolog (TTC4) is a ~44 kDa protein. Co-chaperone that recruits molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1) to nascent polypeptides, facilitating their proper folding into functional proteins. Client proteins include eukaryotic elongation factor eEF2, a key player in cellular translation. Stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. Promotes Sendai virus (SeV)-induced host cell innate immune responses. 1. Crevel, G. et al. (2008) PloS one 3, e0001737. PMID: 18320024 2. Shang, J. et al. (2018) Proteomics 18. PMID: 29251827 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-TTC4 polyclonal antibody at TTC4 on various samples.
Lane 1: 293T cell lysate
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