Anti-Human TUT7 Polyclonal Antibody (HC200014)

Name: Anti-Human TUT7 Polyclonal Antibody
Brand: abinScience
SKU: HC200014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC200014

설명

Anti-Human TUT7 Polyclonal Antibody (HC200014) is a rabbit polyclonal antibody detecting TUT7. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TUT7 (Lys996-Arg1379).

타겟

EC:2.7.7.52, HS2, KIAA1711, TUT7, TUTase 7, Terminal uridylyltransferase 7, ZCCHC6, Zinc finger CCHC domain-containing protein 6

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q5VYS8

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Terminal uridylyltransferase 7 (TUT7) is a ~171 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms.

1. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396

2. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299

3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828

4. Thornton, JE. et al. (2012) RNA (New York, N.Y.) 18, 1875-85. PMID: 22898984

5. Faehnle, CR. et al. (2017) Nature structural & molecular biology 24, 658-665. PMID: 28671666

6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human TUT7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TUT7 Polyclonal Antibody (HC200014)

개요

이미지

참고 문헌

데이터시트

SDS