Anti-Human UBXN1 Polyclonal Antibody (HC343014)

Name: Anti-Human UBXN1 Polyclonal Antibody
Brand: abinScience
SKU: HC343014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC343014

설명

Anti-Human UBXN1 Polyclonal Antibody (HC343014) is a rabbit polyclonal antibody detecting UBXN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human UBXN1 (Asp212-Ser297).

타겟

UBX domain-containing protein 1, UBXN1, SAPK substrate protein 1, UBA/UBX 33.3 kDa protein, SAKS1

정제

Purified by antigen affinity column.

등록번호

Q04323

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

UBX domain-containing protein 1 (UBXN1) is a ~33 kDa protein. Ubiquitin-binding protein that plays a role in the modulation of innate immune response. Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways. Following viral infection, UBXN1 is induced and recruited to the RLR component MAVS. In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome. This function probably serves as a brake to prevent excessive RLR signaling.

1. Wang, P. et al. (2013) Cell reports 3, 1057-70. PMID: 23545497

2. Wang, YB. et al. (2015) The Journal of biological chemistry 290, 10395-405. PMID: 25681446

3. Hu, Y. et al. (2017) PLoS pathogens 13, e1006187. PMID: 28152074

4. Wu-Baer, F. et al. (2010) Molecular and cellular biology 30, 2787-98. PMID: 20351172

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human UBXN1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human UBXN1 Polyclonal Antibody (HC343014)

개요

이미지

참고 문헌

데이터시트

SDS