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Anti-Human UGDH Polyclonal Antibody (HA400014)

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개요
카탈로그 번호HA400014
설명
Anti-Human UGDH Polyclonal Antibody (HA400014) is a rabbit polyclonal antibody detecting UGDH. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human UGDH (Met1-Val494).
타겟 EC:1.1.1.22, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGDH
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 O60701
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

UDP-glucose 6-dehydrogenase (UGDH) is a ~55 kDa protein. Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development.

1. Egger, S. et al. (2011) The Journal of biological chemistry 286, 23877-87. PMID: 21502315
2. Sennett, NC. et al. (2011) Biochemistry 50, 9651-63. PMID: 21961565
3. Egger, S. et al. (2012) The Journal of biological chemistry 287, 2119-29. PMID: 22123821
4. Sennett, NC. et al. (2012) Biochemistry 51, 9364-74. PMID: 23106432
5. Kadirvelraj, R. et al. (2014) Biochemistry 53, 8043-51. PMID: 25478983
6. Beattie, NR. et al. (2017) Biochemistry 56, 202-211. PMID: 27966912
7. Keul, ND. et al. (2018) Nature 563, 584-588. PMID: 30420606
8. Beattie, NR. et al. (2018) Biochemistry 57, 6848-6859. PMID: 30457329
9. Hengel, H. et al. (2020) Nature communications 11, 595. PMID: 32001716
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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