

| 카탈로그 번호 | HY326014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human UROD Polyclonal Antibody (HY326014) is a rabbit polyclonal antibody detecting UROD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human UROD (Met1-Asn367). | ||||||||
| 타겟 | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P06132 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Uroporphyrinogen decarboxylase (UROD) is a ~40 kDa protein. Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. 1. Brady, JJ. et al. (2000) The Journal of investigative dermatology 115, 868-74. PMID: 11069625 2. Phillips, JD. et al. (2001) Blood 98, 3179-85. PMID: 11719352 3. Phillips, JD. et al. (2003) The EMBO journal 22, 6225-33. PMID: 14633982 4. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 5. To-Figueras, J. et al. (2011) The British journal of dermatology 165, 499-505. PMID: 21668429 6. Ged, C. et al. (2002) Archives of dermatology 138, 957-60. PMID: 12071824 | ||||||||
| 참고사항 | For research use only. |
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