Anti-Human USP19 Polyclonal Antibody (HF923014)

Name: Anti-Human USP19 Polyclonal Antibody
Brand: abinScience
SKU: HF923014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HF923014

설명

Anti-Human USP19 Polyclonal Antibody (HF923014) is a rabbit polyclonal antibody detecting USP19 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human USP19 (Lys286-Gln376).

타겟

Deubiquitinating enzyme 19, Ubiquitin thioesterase 19, KIAA0891, ZMYND9, Ubiquitin carboxyl-terminal hydrolase 19, Ubiquitin-specific-processing protease 19, Zinc finger MYND domain-containing protein 9, USP19

정제

Purified by antigen affinity column.

등록번호

O94966

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a ~145 kDa protein. Deubiquitinating enzyme that regulates the degradation of various proteins by removing ubiquitin moieties, thereby preventing their proteasomal degradation. Stabilizes RNF123, which promotes CDKN1B degradation and contributes to cell proliferation. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.

1. Hassink, GC. et al. (2009) EMBO reports 10, 755-61. PMID: 19465887

2. Lee, JG. et al. (2014) The Journal of biological chemistry 289, 3510-7. PMID: 24356957

3. Mei, Y. et al. (2011) The Journal of biological chemistry 286, 35380-35387. PMID: 21849505

4. Altun, M. et al. (2012) The Journal of biological chemistry 287, 1962-9. PMID: 22128162

5. Chai, P. et al. (2021) The Journal of cell biology 220. PMID: 33978709

6. Yu, W. et al. (2024) Journal of Alzheimer's disease : JAD 100, 799-808. PMID: 38943386

7. Lei, CQ. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 259-268. PMID: 31127032

8. Xue, W. et al. (2020) The Biochemical journal 477, 4295-4312. PMID: 33094816

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human USP19 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human USP19 Polyclonal Antibody (HF923014)

개요

이미지

참고 문헌

데이터시트

SDS