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| 카탈로그 번호 | HD622014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human USP34 Polyclonal Antibody (HD622014) is a rabbit polyclonal antibody detecting USP34. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human USP34 (Val1894-Met2239). | ||||||||
| 타겟 | Deubiquitinating enzyme 34, EC:3.4.19.12, KIAA0570, KIAA0729, USP34, Ubiquitin carboxyl-terminal hydrolase 34, Ubiquitin thioesterase 34, Ubiquitin-specific-processing protease 34 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q70CQ2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Ubiquitin carboxyl-terminal hydrolase 34 (USP34) is a ~404 kDa protein. Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. | ||||||||
| 참고사항 | For research use only |
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