Anti-Human VPS41 Polyclonal Antibody (HW488014)

Name: Anti-Human VPS41 Polyclonal Antibody
Brand: abinScience
SKU: HW488014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HW488014

설명

Anti-Human VPS41 Polyclonal Antibody (HW488014) is a rabbit polyclonal antibody detecting VPS41 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human VPS41 (Lys31-Asp361).

타겟

Vacuolar protein sorting-associated protein 41 homolog, VPS41, S53

정제

Purified by antigen affinity column.

등록번호

P49754

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Vacuolar protein sorting-associated protein 41 homolog (VPS41) is a ~98 kDa protein. Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Acts as a component of the HOPS endosomal tethering complex. This complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo.

1. Solinger, JA. et al. (2013) The FEBS journal 280, 2743-57. PMID: 23351085

2. van der Welle, REN. et al. (2021) EMBO molecular medicine 13, e13258. PMID: 33851776

3. Pols, MS. et al. (2013) Traffic (Copenhagen, Denmark) 14, 219-32. PMID: 23167963

4. Lin, X. et al. (2014) Scientific reports 4, 7282. PMID: 25445562

5. Khatter, D. et al. (2015) Journal of cell science 128, 1746-61. PMID: 25908847

6. Radisky, DC. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5662-6. PMID: 9159129

7. Wartosch, L. et al. (2015) Traffic (Copenhagen, Denmark) 16, 727-42. PMID: 25783203

8. Zhang, S. et al. (2023) Nature communications 14, 6360. PMID: 37821429

9. Garg, S. et al. (2011) Immunity 35, 182-93. PMID: 21802320

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human VPS41 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human VPS41 Polyclonal Antibody (HW488014)

개요

이미지

참고 문헌

데이터시트

SDS