Anti-Human WASL Polyclonal Antibody (HT262014)

Name: Anti-Human WASL Polyclonal Antibody
Brand: abinScience
SKU: HT262014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HT262014

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human WASL (Leu21-Arg148).

타겟

N-WASP, WASL, Neural Wiskott-Aldrich syndrome protein

정제

Purified by antigen affinity column.

등록번호

O00401

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Actin nucleation-promoting factor WASL is a ~54 kDa protein. Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization. Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.

1. Wu, X. et al. (2006) Nature cell biology 8, 756-63. PMID: 16767080

2. Vingadassalom, D. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 6754-9. PMID: 19366662

3. Zhang, J. et al. (2009) The Journal of biological chemistry 284, 21659-69. PMID: 19487689

4. Gaucher, JF. et al. (2012) The Journal of biological chemistry 287, 34646-59. PMID: 22847007

5. Aitio, O. et al. (2012) Structure (London, England : 1993) 20, 1692-703. PMID: 22921828

6. Miki, H. et al. (1998) Nature 391, 93-6. PMID: 9422512

7. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human WASL Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human WASL Polyclonal Antibody (HT262014)

개요

이미지

참고 문헌

데이터시트

SDS

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