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| 카탈로그 번호 | HP019014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ZC3H4 (Glu417-Gly503). | ||||||||
| 타겟 | KIAA1064, C19orf7, ZC3H4, Zinc finger CCCH domain-containing protein 4 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UPT8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Zinc finger CCCH domain-containing protein 4 (ZC3H4) is a ~140 kDa protein. RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein. Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome. The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs. 1. Austenaa, LMI. et al. (2021) Nature structural & molecular biology 28, 337-346. PMID: 33767452 2. Estell, C. et al. (2021) eLife 10. PMID: 33913806 | ||||||||
| 참고사항 | For research use only. |
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