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| 카탈로그 번호 | HP537014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ZKSCAN3 (Gly41-Gly176). | ||||||||
| 타겟 | ZNF309, Zinc finger protein 47 homolog, ZKSCAN3, Zfp-47, Zinc finger protein 306, ZSCAN13, ZNF306, Zinc finger protein 309, Zf47, ZFP47, Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9BRR0 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) is a ~60 kDa protein. Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. | ||||||||
| 참고사항 | For research use only. |
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