Anti-Human ZNF143 Polyclonal Antibody (HW561014)

Name: Anti-Human ZNF143 Polyclonal Antibody
Brand: abinScience
SKU: HW561014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW561014

설명

Anti-Human ZNF143 Polyclonal Antibody (HW561014) is a rabbit polyclonal antibody detecting ZNF143 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ZNF143 (Gly263-Thr438).

타겟

STAF, SPH-binding factor, Selenocysteine tRNA gene transcription-activating factor, Zinc finger protein 143, ZNF143, SBF, hStaf

정제

Purified by antigen affinity column.

등록번호

P52747

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Zinc finger protein 143 (ZNF143) is a ~68 kDa protein. Transcription factor that activates expression of genes transcribed by both RNA polymerases II and III, and which is required to safeguard mitochondrial activity. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in thousands of promoters. Activates the gene for selenocysteine tRNA (tRNAsec). Activates expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also activates expression of mRNAs and acts as a key regulator of cell proliferation and differentiation by specifically activating expression of a subset of nuclear-encoded mitochondrial genes, thereby controlling mitochondrial function.

1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243

2. Grossman, CE. et al. (2004) The Journal of biological chemistry 279, 12190-205. PMID: 14702349

3. Yuan, CC. et al. (2007) Molecular and cellular biology 27, 8729-38. PMID: 17938208

4. Vinckevicius, A. et al. (2015) Molecular and cellular biology 35, 4135-46. PMID: 26416877

5. Narducci, DN. et al. (2025) Molecular cell 85, 9-23.e9. PMID: 39708803

6. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341

7. Rincon, JC. et al. (1998) Nucleic acids research 26, 4846-52. PMID: 9776743

8. Myslinski, E. et al. (2006) The Journal of biological chemistry 281, 39953-62. PMID: 17092945

9. Anno, YN. et al. (2011) Nucleic acids research 39, 3116-27. PMID: 21177654

10. Ngondo-Mbongo, RP. et al. (2013) Nucleic acids research 41, 4000-14. PMID: 23408857

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human ZNF143 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ZNF143 Polyclonal Antibody (HW561014)

개요

이미지

참고 문헌

데이터시트

SDS