

| 카탈로그 번호 | HT432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human ZNF263 Polyclonal Antibody (HT432014) is a rabbit polyclonal antibody detecting ZNF263 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ZNF263 (Lys375-Tyr546). | ||||||||
| 타겟 | Zinc finger protein 263, Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12, ZNF263, FPM315, ZKSCAN12 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O14978 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Zinc finger protein 263 (ZNF263) is a ~77 kDa protein. Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. 1. Yu, Z. et al. (2020) Oncogene 39, 3163-3178. PMID: 32051553 2. Weiss, RJ. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 9311-9317. PMID: 32277030 | ||||||||
| 참고사항 | For research use only. |
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