Anti-IGF2BP2 Polyclonal Antibody (HV403014)

Name: Anti-IGF2BP2 Polyclonal Antibody
Brand: abinScience
SKU: HV403014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HV403014

설명

Anti-IGF2BP2 Polyclonal Antibody (HV403014) is a rabbit polyclonal antibody detecting IGF2BP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human IGF2BP2 (Ser141-Pro384).

타겟

Hepatocellular carcinoma autoantigen p62, IMP2, IGF-II mRNA-binding protein 2, IMP-2, VICKZ2, VICKZ family member 2, IGF2BP2, IGF2 mRNA-binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2

정제

Purified by antigen affinity column.

등록번호

Q9Y6M1

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a ~66 kDa protein. RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

1. Huang, H. et al. (2018) Nature cell biology 20, 285-295. PMID: 29476152

2. Nielsen, J. et al. (1999) Molecular and cellular biology 19, 1262-70. PMID: 9891060

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-IGF2BP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-IGF2BP2 Polyclonal Antibody (HV403014)

개요

이미지

참고 문헌

데이터시트

SDS

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