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| 카탈로그 번호 | HC296014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ILF3 Polyclonal Antibody (HC296014) is a rabbit polyclonal antibody detecting ILF3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ILF3 (Tyr672-Tyr891). | ||||||||
| 타겟 | ILF3, MPHOSPH4, DRBP76, TCP80, DRBF, Translational control protein 80, M-phase phosphoprotein 4, Nuclear factor associated with dsRNA, NF90, NFAR, MPP4, NF-AT-90, Double-stranded RNA-binding protein 76, Interleukin enhancer-binding factor 3, Nuclear factor of activated T-cells 90 kDa | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q12906 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interleukin enhancer-binding factor 3 (ILF3) is a ~95 kDa protein. RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs. As a consequence, participates in a wide range of transcriptional and post-transcriptional processes. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. 1. Li, X. et al. (2017) Molecular cell 67, 214-227.e7. PMID: 28625552 2. Tran, H. et al. (2004) Molecular cell 13, 101-11. PMID: 14731398 3. Harashima, A. et al. (2010) Genes & development 24, 2640-53. PMID: 21123651 4. Dou, S. et al. (2021) eLife 10. PMID: 34110282 | ||||||||
| 참고사항 | For research use only. |
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