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| 카탈로그 번호 | HW565014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-IREB2 Polyclonal Antibody (HW565014) is a rabbit polyclonal antibody detecting IREB2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human IREB2 (Pro39-Ser281). | ||||||||
| 타겟 | IRP2, Iron-responsive element-binding protein 2, IREB2, IRE-BP 2, Iron regulatory protein 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P48200 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Iron-responsive element-binding protein 2 (IREB2) is a ~105 kDa protein. RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. | ||||||||
| 참고사항 | For research use only. |
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