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| 카탈로그 번호 | VK453063 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Lassa virus (LASV) | ||||||
| 응용 분야 | ELISA, Neutralization, WB, FCM | ||||||
| 숙주 종 | Human | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG1, kappa | ||||||
| 클론 ID | 12.1F | ||||||
| 테스트된 응용 분야 | WB | ||||||
| 타겟 | Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P08669 | ||||||
| RRID | Anti-LASV GPC Antibody (12.1F) (abinScience Cat# VK453063, RRID:AB_3725214) |
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| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 배경 | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 | ||||||
| 참고사항 | For research use only. |
Detects LASV GPC protein (VK453011) in indirect ELISAs.
Detects Recombinant LASV GPC Protein, N-His & C-TwinStrep (Cat No.: VK453011) in indirect ELISA.
SDS-PAGE for Anti-LASV GPC Antibody (12.1F).
Western blot analysis was performed using anti-Lassa virus GPC monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant LASV GPC (Catalog No: VK453011)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
