

| 카탈로그 번호 | JN177014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Magnaporthe oryzae ATG8 Polyclonal Antibody (JN177014) is a rabbit polyclonal antibody detecting ATG8. Suitable for Phaeosphaeria nodorum, Sclerotinia sclerotiorum, Aspergillus oryzae, Coccidioides immitis, Glomerella lagenarium, Aspergillus fumigatus, Pyricularia oryzae, Colletotrichum lindemuthianum, Neurospora crassa, Aspergillus terreus, Gibberella zeae, Penicillium rubens, Botryotinia fuckeliana, Beauveria bassiana, Neosartorya fischeri, Aspergillus clavatus, Podospora anserina, Emericella nidulans, Cochliobolus heterostrophus, Chaetomium globosum, and Aspergillus niger.
Highlights
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| 종 반응성 | Phaeosphaeria nodorum, Sclerotinia sclerotiorum, Aspergillus oryzae, Aspergillus niger | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Magnaporthe oryzae ATG8 (Met1-Phe115). | ||||||||
| 타겟 | ATG8, Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q51MW4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Autophagy-related protein 8 (ATG8) is a ~14 kDa protein. Ubiquitin-like modifier involved in autophagosome formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. | ||||||||
| 참고사항 | For research use only |
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