Anti-MAPK11 Polyclonal Antibody (HS729014)

Name: Anti-MAPK11 Polyclonal Antibody
Brand: abinScience
SKU: HS729014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HS729014

설명

Anti-MAPK11 Polyclonal Antibody (HS729014) is a rabbit polyclonal antibody detecting MAPK11 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MAPK11 (Leu24-Phe308).

타겟

MAP kinase 11, Mitogen-activated protein kinase p38 beta, MAPK 11, Mitogen-activated protein kinase 11, PRKM11, SAPK2B, Stress-activated protein kinase 2b, MAP kinase p38 beta, MAPK11, p38b, p38-2, SAPK2, SAPK2b

정제

Purified by antigen affinity column.

등록번호

Q15759

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Mitogen-activated protein kinase 11 (MAPK11) is a ~41 kDa protein. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK11 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK11 functions are mostly redundant with those of MAPK14. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets.

1. Shi, Y. et al. (2002) Biological chemistry 383, 1519-36. PMID: 12452429

2. Cuadrado, A. et al. (2010) The Biochemical journal 429, 403-17. PMID: 20626350

3. Robinson, KS. et al. (2022) Science (New York, N.Y.) 377, 328-335. PMID: 35857590

4. Deak, M. et al. (1998) The EMBO journal 17, 4426-41. PMID: 9687510

5. Scheper, GC. et al. (2001) Molecular and cellular biology 21, 743-54. PMID: 11154262

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-MAPK11 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MAPK11 Polyclonal Antibody (HS729014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기