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| 카탈로그 번호 | VK669023 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Lake Victoria marburgvirus (MARV) (Marburg virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1 | ||||
| 클론 ID | MR78 | ||||
| 타겟 | Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q1PDC7 | ||||
| RRID | Anti-MARV GP/Envelope glycoprotein Antibody (MR78) (abinScience Cat# VK669023, RRID:AB_3727017) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Envelope glycoprotein (GP) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection). | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-MARV GP/Envelope glycoprotein Antibody (MR78).
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