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| 카탈로그 번호 | HF785014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-MB Polyclonal Antibody (HF785014) is a rabbit polyclonal antibody detecting MB in ELISA, IHC, WB. Suitable for Human, Aotus trivirgatus, Balaena mysticetus, Balaenoptera edeni, and Callithrix jacchus.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MB (Met1-Gly154). | ||||||||
| 타겟 | Myoglobin, MB | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P02144 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Myoglobin (MB) is a ~17 kDa protein. Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. 1. Olivé, M. et al. (2019) Nature communications 10, 1396. PMID: 30918256 2. Hofbauer, S. et al. (2022) The FEBS journal 289, 1105-1117. PMID: 34679218 3. Quesnelle, K. et al. (2020) Nitric oxide : biology and chemistry 104-105, 36-43. PMID: 32891753 | ||||||||
| 참고사항 | For research use only. |
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