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| 카탈로그 번호 | HW819014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-METAP2 Polyclonal Antibody (HW819014) is a rabbit polyclonal antibody detecting METAP2 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant METAP2 (Gly132-Tyr478). | ||||||||
| 타겟 | Methionine aminopeptidase 2, MAP 2, MetAP 2, EC:3.4.11.18, Initiation factor 2-associated 67 kDa glycoprotein, p67, p67eIF2, Peptidase M, METAP2, MNPEP, P67EIF2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P50579, P38062, O08663 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Methionine aminopeptidase 2 is a ~52 kDa protein. Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. | ||||||||
| 참고사항 | For research use only |
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