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| 카탈로그 번호 | ZA029023 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Centruroides (Mexican scorpion) | ||||
| 응용 분야 | ELISA, Neutralization, SPR | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a | ||||
| 클론 ID | 4B | ||||
| 타겟 | Beta-toxin Cl13, CliNaTxBet37, Beta-toxin Cb3, Centruroides limpidus (Mexican scorpion), Centruroides baergi (Scorpion) (Centruroides nigrovariatus baergi) | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | C0HK69, C0HLR5 | ||||
| RRID | Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (4B) (abinScience Cat# ZA029023, RRID:AB_3729011) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Beta-toxin Cl13 (Cb3) is a ~8 kDa protein. Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Inhibits sodium channels Nav1.4/SCN4A, Nav1.5/SCN5A and Nav1.6/SCN8A. Also has a weak inhibitory effect on Nav1.2/SCN2A. Is lethal to mice. 1. Olamendi-Portugal, T. et al. (2017) Peptides 87, 34-40. PMID: 27871874 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (4B)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
