Anti-MFN2 Polyclonal Antibody (HF769014)

Name: Anti-MFN2 Polyclonal Antibody
Brand: abinScience
SKU: HF769014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF769014

설명

Anti-MFN2 Polyclonal Antibody (HF769014) is a rabbit polyclonal antibody detecting MFN2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MFN2 (His20-Arg400).

타겟

Transmembrane GTPase MFN2, Mitofusin-2, KIAA0214, CPRP1, MFN2

정제

Purified by antigen affinity column.

등록번호

O95140

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Mitofusin-2 (MFN2) is a ~86 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes.

1. Santel, A. et al. (2001) Journal of cell science 114, 867-74. PMID: 11181170

2. Rojo, M. et al. (2002) Journal of cell science 115, 1663-74. PMID: 11950885

3. Casasnovas, C. et al. (2010) Journal of medical genetics 47, 249-56. PMID: 19889647

4. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

5. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303

6. Chen, Y. et al. (2013) Science (New York, N.Y.) 340, 471-5. PMID: 23620051

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-MFN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MFN2 Polyclonal Antibody (HF769014)

개요

이미지

참고 문헌

데이터시트

SDS

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