

| 카탈로그 번호 | HV516014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-MGLL Polyclonal Antibody (HV516014) is a rabbit polyclonal antibody detecting MGLL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MGLL (Met1-Pro303). | ||||||||
| 타겟 | Lysophospholipase-like, MGLL, Monoacylglycerol lipase, Lysophospholipase homolog, MGL, Monoglyceride lipase, HU-K5, MAGL | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q99685 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. 1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917 2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151 5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842 | ||||||||
| 참고사항 | For research use only. |
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